Villanova opened the game with a 12‑0 run, pulling ahead 16‑5 by the end of the first quarter. The Wildcats never trailed and never fell below a 12‑point margin after the second half began.
Marquette committed 22 turnovers, nine in the first quarter, and struggled to generate offense in the middle 20 minutes. The game ended 64‑39, a blowout that left Marquette with a disappointing finish after a competitive outing against UConn eight days earlier. Marquette will face Xavier on Wednesday night for their final home game.