Despite finishing 81-81 with a negative run differential (-32), the Astros secured the AL West title and are now favored against the upstart White Sox. Chicago enters the postseason after three consecutive 100-loss seasons, with their last playoff series victory coming all the way back in 2005.
The Astros, World Series winners in 2017 and 2022, have won five of seven regular-season matchups against Chicago this year, including three of the last four. newsbetting.bond
